ZFIN is now using GRCz12tu for Genomic Data
Gene
exoc6b
- ID
- ZDB-GENE-060929-132
- Name
- exocyst complex component 6B
- Symbol
- exoc6b Nomenclature History
- Previous Names
-
- fa55b02
- wu:fa55b02
- zgc:153610
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in Golgi to plasma membrane transport; exocytosis; and intracellular protein transport. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia with joint laxity type 3. Orthologous to human EXOC6B (exocyst complex component 6B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spondyloepimetaphyseal dysplasia with joint laxity type 3 | Alliance | Spondyloepimetaphyseal dysplasia with joint laxity, type 3 | 618395 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR046361 | Exocyst complex subunit EXOC6/Sec15, C-terminal |
| Domain | IPR048359 | Exocyst complex component EXOC6/Sec15, N-terminal domain |
| Family | IPR007225 | Exocyst complex component EXOC6/Sec15 |
| Homologous_superfamily | IPR042044 | EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 |
| Homologous_superfamily | IPR042045 | Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 |
Domain Details Per Protein
| Protein | Additional Resources | Length | EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 | Exocyst complex component EXOC6/Sec15 | Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 | Exocyst complex component EXOC6/Sec15, N-terminal domain | Exocyst complex subunit EXOC6/Sec15, C-terminal |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q814 | InterPro | 816 | |||||
| UniProtKB:A0A8M3AU30 | InterPro | 806 | |||||
| UniProtKB:A0A0R4ILM6 | InterPro | 802 | |||||
| UniProtKB:A0A8M9QH78 | InterPro | 812 | |||||
| UniProtKB:A0AB32TRV6 | InterPro | 784 | |||||
| UniProtKB:A0AC58G0F1 | InterPro | 812 | |||||
| UniProtKB:A0AC58G0F9 | InterPro | 784 | |||||
| UniProtKB:A0AC58G0G0 | InterPro | 774 | |||||
| UniProtKB:A0AC58G0N7 | InterPro | 708 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
exoc6b-201
(1)
|
Ensembl | 4,170 nt | ||
| mRNA |
exoc6b-202
(1)
|
Ensembl | 735 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers