ZFIN is now using GRCz12tu for Genomic Data
Gene
minpp1a
- ID
- ZDB-GENE-060929-1194
- Name
- multiple inositol-polyphosphate phosphatase 1a
- Symbol
- minpp1a Nomenclature History
- Previous Names
-
- zgc:153026
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable inositol hexakisphosphate phosphatase activity; inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity; and inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity. Predicted to be located in plasma membrane. Predicted to be active in endoplasmic reticulum lumen and extracellular region. Human ortholog(s) of this gene implicated in papillary thyroid carcinoma; pontocerebellar hypoplasia type 16; and thyroid gland disease. Orthologous to human MINPP1 (multiple inositol-polyphosphate phosphatase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| follicular thyroid carcinoma | Alliance | {Thyroid carcinoma, follicular} | 188470 |
| pontocerebellar hypoplasia type 16 | Alliance | Pontocerebellar hypoplasia, type 16 | 619527 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Histidine acid phosphatase, eukaryotic | Histidine phosphatase superfamily | Histidine phosphatase superfamily, clade-2 |
|---|---|---|---|---|---|
| UniProtKB:Q08CJ4 | InterPro | 459 | |||
| UniProtKB:A0A8M2B5D6 | InterPro | 458 | |||
| UniProtKB:A0AC58HN82 | InterPro | 458 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
minpp1a-201
(1)
|
Ensembl | 2,385 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers