ZFIN is now using GRCz12tu for Genomic Data
Gene
gon4la
- ID
- ZDB-GENE-060503-728
- Name
- gon-4 like a
- Symbol
- gon4la Nomenclature History
- Previous Names
-
- si:dkey-27c15.3
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in chromosome. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in hypertension and intellectual disability. Orthologous to several human genes including GON4L (gon-4 like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Tsai et al., 2026
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Tsai et al., 2026
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Li-Takada-Miyake syndrome | Alliance | Li-Takada-Miyake syndrome | 621212 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| intellectual disability | gon4lann2112/nn2112 | standard conditions | Tsai et al., 2026 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR049257 | Gon4l/CASP8AP2, myb-like domain |
| Family | IPR052435 | YY1-Associated Transcriptional Regulator |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR036600 | Paired amphipathic helix superfamily |
| Repeat | IPR003822 | Paired amphipathic helix |
Domain Details Per Protein
| Protein | Additional Resources | Length | Gon4l/CASP8AP2, myb-like domain | Homedomain-like superfamily | Paired amphipathic helix | Paired amphipathic helix superfamily | YY1-Associated Transcriptional Regulator |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32T8L6 | InterPro | 1620 | |||||
| UniProtKB:A0A8M1RJB6 | InterPro | 1602 | |||||
| UniProtKB:A0AC58I0W7 | InterPro | 1594 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-27c15.3-201
(1)
|
Ensembl | 3,099 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers