dcdc2b

ID

ZDB-GENE-051113-124

Name

doublecortin domain containing 2B

Symbol

dcdc2b Nomenclature History

Previous Names

zgc:123267

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Acts upstream of or within pronephros development; sensory organ development; and sensory perception of sound. Is expressed in otic vesicle. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autosomal recessive nonsyndromic deafness 66; dyslexia; nephronophthisis 19; and sclerosing cholangitis. Orthologous to several human genes including DCDC2B (doublecortin domain containing 2B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dcdc2b Human Ortholog

No data available

Associated With dcdc2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003533	Doublecortin domain
Homologous_superfamily	IPR036572	Doublecortin domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M6Z1P8	InterPro	454
UniProtKB:A0A8M6Z961	InterPro	431
UniProtKB:A0A8M6Z9L0	InterPro	447
UniProtKB:A0AC58H1B3	InterPro	447
UniProtKB:A0AC58H1B5	InterPro	454
UniProtKB:A0AC58H1C2	InterPro	424
UniProtKB:A0AC58H1C3	InterPro	424
UniProtKB:A0AC58H1C4	InterPro	424
UniProtKB:A0AC58H1C7	InterPro	431
UniProtKB:A0AC58H1C8	InterPro	424
UniProtKB:A0AC58H1C9	InterPro	447
UniProtKB:A0AC58H1D1	InterPro	431
UniProtKB:A0AC58H1E7	InterPro	431