ZFIN is now using GRCz12tu for Genomic Data
Gene
phf2
- ID
- ZDB-GENE-050302-10
- Name
- PHD finger protein 2
- Symbol
- phf2 Nomenclature History
- Previous Names
-
- phf8
- im:4200679
- wu:fa14c10
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including histone H3K4me3 reader activity; histone demethylase activity; and transition metal ion binding activity. Predicted to be involved in negative regulation of rDNA heterochromatin formation; protein demethylation; and transcription initiation-coupled chromatin remodeling. Predicted to be located in kinetochore and nucleolus. Predicted to be active in nucleus. Orthologous to human PHF2 (PHD finger protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR003347 | JmjC domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR041070 | Jumonji, helical domain |
| Family | IPR050690 | JHDM1 Histone Demethylase |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Additional Resources | Length | JHDM1 Histone Demethylase | JmjC domain | Jumonji, helical domain | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6P949 | InterPro | 1063 | ||||||||
| UniProtKB:A0A8M2BH62 | InterPro | 1059 | ||||||||
| UniProtKB:A0A8M2BGL0 | InterPro | 1066 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers