ZFIN is now using GRCz12tu for Genomic Data
Gene
gtpbp2b
- ID
- ZDB-GENE-050208-373
- Name
- GTP binding protein 2b
- Symbol
- gtpbp2b Nomenclature History
- Previous Names
-
- gtpbp2
- si:ch211-151i8.2 (1)
- si:dkeyp-34c12.3
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in translational elongation. Human ortholog(s) of this gene implicated in disease of mental health. Orthologous to human GTPBP2 (GTP binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7149726 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Jaberi-Elahi syndrome | 617988 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000795 | Translational (tr)-type GTP-binding domain |
| Domain | IPR004161 | Translation elongation factor EFTu-like, domain 2 |
| Domain | IPR035531 | GTP binding protein 1-like, GTP-binding domain |
| Family | IPR050055 | Elongation factor Tu GTPase |
| Homologous_superfamily | IPR009000 | Translation protein, beta-barrel domain superfamily |
| Homologous_superfamily | IPR009001 | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | Elongation factor Tu GTPase | GTP binding protein 1-like, GTP-binding domain | P-loop containing nucleoside triphosphate hydrolase | Translational (tr)-type GTP-binding domain | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal | Translation elongation factor EFTu-like, domain 2 | Translation protein, beta-barrel domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1PAI6 | InterPro | 605 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gtpbp2b-201
(1)
|
Ensembl | 1,904 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers