ZFIN is now using GRCz12tu for Genomic Data
Gene

picalma

ID
ZDB-GENE-040426-761
Name
phosphatidylinositol binding clathrin assembly protein a
Symbol
picalma Nomenclature History
Previous Names
  • picalm
  • zgc:55615
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable 1-phosphatidylinositol binding activity and clathrin binding activity. Predicted to be involved in clathrin coat assembly and clathrin-dependent endocytosis. Predicted to be located in several cellular components, including Golgi apparatus; clathrin-coated pit; and clathrin-coated vesicle. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human PICALM (phosphatidylinositol binding clathrin assembly protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With picalma Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
acute myeloid leukemia Alliance Leukemia, acute myeloid, somatic 601626
Associated With picalma Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011417 AP180 N-terminal homology (ANTH) domain
Domain IPR013809 ENTH domain
Family IPR045192 Clathrin coat assembly protein AP180-like
Homologous_superfamily IPR008942 ENTH/VHS
Homologous_superfamily IPR014712 ANTH domain superfamily
Domain Details Per Protein
Protein Additional Resources Length ANTH domain superfamily AP180 N-terminal homology (ANTH) domain Clathrin coat assembly protein AP180-like ENTH domain ENTH/VHS
UniProtKB:A0A8M3B3B6 InterPro 728
UniProtKB:A0A8M3B3B4 InterPro 710
UniProtKB:A0A8M9Q5T8 InterPro 718
UniProtKB:A0A8M9PTF3 InterPro 733
UniProtKB:A0A8M3BD23 InterPro 615
UniProtKB:A0A8M9QKL0 InterPro 665
UniProtKB:A0A8M3AWT2 InterPro 732
UniProtKB:A0A8M9QGG0 InterPro 640
UniProtKB:A0A8M9QKK5 InterPro 740
UniProtKB:A0A8M3B698 InterPro 579
UniProtKB:A0A8M9PTF8 InterPro 638
UniProtKB:A0A8M9Q5T5 InterPro 744
UniProtKB:A0A8M3AWV7 InterPro 736
UniProtKB:A0A8M9Q5U3 InterPro 736
UniProtKB:A0A8M9QKL4 InterPro 630
UniProtKB:A0A8M9PTG3 InterPro 623
UniProtKB:A0A8M3AWV9 InterPro 622
UniProtKB:F1QKW9 InterPro 589
UniProtKB:Q7ZVU6 InterPro 589
UniProtKB:A0A8M9QGG5 InterPro 627
UniProtKB:A0A8M9QGF6 InterPro 740
UniProtKB:A0A8M9QBW5 InterPro 716
UniProtKB:A0A8M3B694 InterPro 725
UniProtKB:A0A8M9QBX0 InterPro 634
UniProtKB:A0A8M9QBW1 InterPro 742
UniProtKB:A0A8M9Q5U0 InterPro 634
UniProtKB:A0AB13A7H5 InterPro 657
UniProtKB:A0AB32TVP3 InterPro 630
UniProtKB:A0AB32TVQ1 InterPro 626
UniProtKB:A0AB32TWE9 InterPro 593
UniProtKB:A0AB32TXZ7 InterPro 596
UniProtKB:A0AB32TYD0 InterPro 642
UniProtKB:A0AB32TYZ4 InterPro 604
UniProtKB:A0AB32U0M1 InterPro 600
UniProtKB:A0AB32U193 InterPro 699
UniProtKB:A0AB32U296 InterPro 646
UniProtKB:A0AB32U3C2 InterPro 706
UniProtKB:A0AC58GIY7 InterPro 674
UniProtKB:A0AC58GIZ5 InterPro 701
UniProtKB:A0AC58GIZ6 InterPro 678
UniProtKB:A0AC58GIZ9 InterPro 704
UniProtKB:A0AC58GJ01 InterPro 700
UniProtKB:A0AC58GJ04 InterPro 627
UniProtKB:A0AC58GJ05 InterPro 627
UniProtKB:A0AC58GJ07 InterPro 649
UniProtKB:A0AC58GJ08 InterPro 642
UniProtKB:A0AC58GJ13 InterPro 686
UniProtKB:A0AC58GJ17 InterPro 616
UniProtKB:A0AC58GJ18 InterPro 597
UniProtKB:A0AC58GJ21 InterPro 597
UniProtKB:A0AC58GJ24 InterPro 608
UniProtKB:A0AC58GJ27 InterPro 630
UniProtKB:A0AC58GJ36 InterPro 604
UniProtKB:A0AC58GJ39 InterPro 700
UniProtKB:A0AC58GJ43 InterPro 600
UniProtKB:A0AC58GJ44 InterPro 708
UniProtKB:A0AC58GJ46 InterPro 667
UniProtKB:A0AC58GJ47 InterPro 693
UniProtKB:A0AC58GJ54 InterPro 635
UniProtKB:A0AC58GJ56 InterPro 626
UniProtKB:A0AC58GJ57 InterPro 623
UniProtKB:A0AC58GJ58 InterPro 650
UniProtKB:A0AC58GJ59 InterPro 634
UniProtKB:A0AC58GJ67 InterPro 661
UniProtKB:A0AC58GJ68 InterPro 596
UniProtKB:A0AC58GJ69 InterPro 608
UniProtKB:A0AC58GJ70 InterPro 622
UniProtKB:A0AC58GJ71 InterPro 589
UniProtKB:A0AC58GJ72 InterPro 712
UniProtKB:A0AC58GJ74 InterPro 704
UniProtKB:A0AC58GJ77 InterPro 604
UniProtKB:A0AC58GJ79 InterPro 623
UniProtKB:A0AC58GJ82 InterPro 649
UniProtKB:A0AC58GJ89 InterPro 653
UniProtKB:A0AC58GJ93 InterPro 615
UniProtKB:A0AC58GJA1 InterPro 623
UniProtKB:A0AC58GJD5 InterPro 657
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA picalma-201 (1)
Ensembl
Ensembl 3,477 nt
ZFIN BLAST
mRNA picalma-202 (1)
Ensembl
Ensembl 2,222 nt
ZFIN BLAST
mRNA picalma-203 (1)
Ensembl
Ensembl 2,220 nt
ZFIN BLAST
mRNA picalma-204 (1)
Ensembl
Ensembl 825 nt
ZFIN BLAST
mRNA picalma-205 (1)
Ensembl
Ensembl 566 nt
ZFIN BLAST
mRNA picalma-206 (1)
Ensembl
Ensembl 2,534 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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