pemt

ID

ZDB-GENE-040426-719

Name

phosphatidylethanolamine N-methyltransferase

Symbol

pemt Nomenclature History

Previous Names

zgc:55479 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable phosphatidyl-N-methylethanolamine N-methyltransferase activity. Predicted to be involved in phosphatidylcholine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane and mitochondrial membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human PEMT (phosphatidylethanolamine N-methyltransferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55479 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pemt Human Ortholog

No data available

Associated With pemt Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR007318	Phospholipid methyltransferase
Family	IPR024960	Phosphatidyl-N-methylethanolamine/Phosphatidylethanolamine N-methyltransferase

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:Q7ZVZ2	InterPro	229
UniProtKB:A0AC58GV01	InterPro	219
UniProtKB:A0AC58GV04	InterPro	204
UniProtKB:A0AC58GV07	InterPro	203
UniProtKB:A0AC58GV08	InterPro	203
UniProtKB:A0AC58GV13	InterPro	178
UniProtKB:A0AC58GV14	InterPro	194