ZFIN is now using GRCz12tu for Genomic Data
Gene
ppp2r3c
- ID
- ZDB-GENE-040426-715
- Name
- protein phosphatase 2, regulatory subunit B'', gamma
- Symbol
- ppp2r3c Nomenclature History
- Previous Names
-
- zgc:55473
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium ion binding activity. Predicted to be involved in cortical cytoskeleton organization; microtubule cytoskeleton organization; and regulation of B cell activation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in centrosome. Human ortholog(s) of this gene implicated in fundus dystrophy and spermatogenic failure 36. Orthologous to human PPP2R3C (protein phosphatase 2 regulatory subunit B''gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55473 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spermatogenic failure 36 | Alliance | Spermatogenic failure 36 | 618420 |
| Myoectodermal gonadal dysgenesis syndrome | 618419 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | EF-Hand 1, calcium-binding site | EF-hand domain pair | PP2A regulatory subunit B'', EF-hand domain | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma |
|---|---|---|---|---|---|---|
| UniProtKB:B2GT25 | InterPro | 457 | ||||
| UniProtKB:Q803V3 | InterPro | 457 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppp2r3c-201
(1)
|
Ensembl | 1,684 nt | ||
| ncRNA |
ppp2r3c-002
(1)
|
Ensembl | 970 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers