ZFIN is now using GRCz12tu for Genomic Data
Gene
exoc7
- ID
- ZDB-GENE-040426-2752
- Name
- exocyst complex component 7
- Symbol
- exoc7 Nomenclature History
- Previous Names
-
- zgc:56575 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Involved in telencephalon development. Predicted to be part of exocyst. Used to study microcephaly. Human ortholog(s) of this gene implicated in epilepsy. Orthologous to human EXOC7 (exocyst complex component 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56575 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Coulter et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with seizures and brain atrophy | 619072 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| microcephaly | exoc7mh111/mh111 | standard conditions | Coulter et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cullin repeat-like-containing domain superfamily | Exocyst complex component Exo70 | Exocyst complex subunit Exo70, C-terminal |
|---|---|---|---|---|---|
| UniProtKB:U3JAX5 | InterPro | 695 | |||
| UniProtKB:A0A8M2BKA5 | InterPro | 686 | |||
| UniProtKB:U3JAN6 | InterPro | 652 | |||
| UniProtKB:A0A8M3AYR4 | InterPro | 690 | |||
| UniProtKB:A0A8M9Q897 | InterPro | 677 | |||
| UniProtKB:Q7ZTX5 | InterPro | 673 | |||
| UniProtKB:A0A8M2BKR2 | InterPro | 665 | |||
| UniProtKB:A0A8M2BK81 | InterPro | 686 | |||
| UniProtKB:A0A2R8QNA9 | InterPro | 703 | |||
| UniProtKB:A0A286Y9B1 | InterPro | 699 | |||
| UniProtKB:U3JB38 | InterPro | 682 | |||
| UniProtKB:A0AB32U114 | InterPro | 716 | |||
| UniProtKB:A0AC58GV83 | InterPro | 632 | |||
| UniProtKB:A0AC58GVA0 | InterPro | 611 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
exoc7-201
(1)
|
Ensembl | 2,279 nt | ||
| mRNA |
exoc7-202
(1)
|
Ensembl | 3,024 nt | ||
| mRNA |
exoc7-203
(1)
|
Ensembl | 2,071 nt | ||
| mRNA |
exoc7-204
(1)
|
Ensembl | 2,571 nt | ||
| mRNA |
exoc7-205
(1)
|
Ensembl | 267 nt | ||
| mRNA |
exoc7-206
(1)
|
Ensembl | 2,216 nt | ||
| mRNA |
exoc7-207
(1)
|
Ensembl | 2,961 nt | ||
| mRNA |
exoc7-208
(1)
|
Ensembl | 2,973 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers