ZFIN is now using GRCz12tu for Genomic Data
Gene
stxbp2
- ID
- ZDB-GENE-040426-2482
- Name
- syntaxin binding protein 2
- Symbol
- stxbp2 Nomenclature History
- Previous Names
-
- zgc:85807
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable syntaxin-1 binding activity and syntaxin-3 binding activity. Predicted to be involved in intracellular protein transport and presynaptic dense core vesicle exocytosis. Predicted to be located in membrane and presynapse. Predicted to be active in plasma membrane and secretory granule. Is expressed in brain; epidermis; liver; periderm; and sensory system. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 5. Orthologous to human STXBP2 (syntaxin binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85807 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial hemophagocytic lymphohistiocytosis 5 | Alliance | Hemophagocytic lymphohistiocytosis, familial, 5, with or without microvillus inclusion disease | 613101 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Sec1-like, domain 1 | Sec1-like, domain 2 | Sec1-like, domain 3a | Sec1-like protein | Sec1-like superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PTU9 | InterPro | 343 | |||||
| UniProtKB:Q6NUX6 | InterPro | 595 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stxbp2-201
(1)
|
Ensembl | 2,529 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers