ZFIN is now using GRCz12tu for Genomic Data
Gene
tctn2
- ID
- ZDB-GENE-030131-751
- Name
- tectonic family member 2
- Symbol
- tctn2 Nomenclature History
- Previous Names
-
- fb44f11
- si:ch211-89f7.3
- wu:fb44f11
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within determination of left/right symmetry. Human ortholog(s) of this gene implicated in Joubert syndrome 24 and Meckel syndrome 8. Orthologous to human TCTN2 (tectonic family member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Liu et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Joubert syndrome 24 | Alliance | Joubert syndrome 24 | 616654 |
| Meckel syndrome 8 | Alliance | ?Meckel syndrome 8 | 613885 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Tectonic-1-3 | Tectonic-1-3 domain | Tectonic-1-3, N-terminal domain |
|---|---|---|---|---|---|
| UniProtKB:F1R5E2 | InterPro | 702 | |||
| UniProtKB:A0AC58JNN9 | InterPro | 707 | |||
| UniProtKB:A0ACD6B6H4 | InterPro | 702 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers