ZFIN is now using GRCz12tu for Genomic Data
Gene
ddx61
- ID
- ZDB-GENE-030131-6611
- Name
- DEAD (Asp-Glu-Ala-Asp) box helicase 61
- Symbol
- ddx61 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable mRNA binding activity. Acts upstream of or within cytoplasmic stress granule assembly and response to heat. Located in cytoplasmic ribonucleoprotein granule. Human ortholog(s) of this gene implicated in intellectual disability. Orthologous to human DDX6 (DEAD-box helicase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zampedri et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000629 | ATP-dependent RNA helicase DEAD-box, conserved site |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR011545 | DEAD/DEAH-box helicase domain |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR014014 | RNA helicase, DEAD-box type, Q motif |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | ATP-dependent RNA helicase DEAD-box, conserved site | DEAD/DEAH-box helicase domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | RNA helicase, DEAD-box type, Q motif |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7F1G8 | InterPro | 483 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers