ZFIN is now using GRCz12tu for Genomic Data
Gene
trim37
- ID
- ZDB-GENE-030131-2957
- Name
- tripartite motif containing 37
- Symbol
- trim37 Nomenclature History
- Previous Names
-
- fc22d08
- si:ch211-251d10.4
- wu:fc22d08 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable zinc ion binding activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in bone development disease and mulibrey nanism. Orthologous to human TRIM37 (tripartite motif containing 37).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mulibrey nanism | Alliance | Mulibrey nanism | 253250 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000315 | B-box-type zinc finger |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR002083 | MATH/TRAF domain |
| Domain | IPR003649 | B-box, C-terminal |
| Domain | IPR037299 | TRIM37, MATH domain |
| Family | IPR053003 | TRIM/RBCC E3 ubiquitin-protein ligases |
| Homologous_superfamily | IPR008974 | TRAF-like |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Additional Resources | Length | B-box, C-terminal | B-box-type zinc finger | MATH/TRAF domain | TRAF-like | TRIM37, MATH domain | TRIM/RBCC E3 ubiquitin-protein ligases | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7FBZ8 | InterPro | 957 | ||||||||
| UniProtKB:A0A8M9PU88 | InterPro | 952 | ||||||||
| UniProtKB:A0ACD6B767 | InterPro | 957 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
trim37-201
(1)
|
Ensembl | 4,732 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers