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Phenotype Figure Summary
Marker:
cyp11a1.2
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Li
et al.
, 2019
Fig. 1
cyp11a1.2
sh565/sh565
whole organism visually-mediated background adaptation decreased process quality, abnormal
Fig. 2
cyp11a1.2
sh565/sh565
whole organism
fkbp5
expression decreased amount, abnormal
whole organism
pck1
expression decreased amount, abnormal
whole organism cortisol decreased amount, abnormal
Fig. 3
cyp11a1.2
sh565/sh565
hypophysis
pomca
expression increased amount, abnormal
whole organism
pomca
expression increased amount, abnormal
Fig. 4
cyp11a1.2
sh565/sh565
male organism development of secondary female sexual characteristics increased process quality, abnormal
male organism increased length, abnormal
male organism increased weight, abnormal
male organism urogenital papilla decreased size, abnormal
testis
gh1
expression increased amount, abnormal
whole organism male, abnormal
Fig. 5
cyp11a1.2
sh565/sh565
liver
cyp2k22
expression decreased amount, abnormal
liver
fkbp5
expression decreased amount, abnormal
liver
pck1
expression decreased amount, abnormal
whole organism 11-oxotestosterone decreased amount, abnormal
whole organism 5alpha-androst-1-ene-3,17-dione decreased amount, abnormal
whole organism adrenosterone decreased amount, abnormal
whole organism cortisol decreased amount, abnormal
whole organism testosterone decreased amount, abnormal
Fig. 6
cyp11a1.2
sh565/sh565
male organism male sterile, abnormal
male organism seminiferous tubule disorganized, abnormal
male organism sperm decreased amount, abnormal
testis spermatocyte decreased amount, abnormal
testis spermatogonium increased amount, abnormal
Fig. 7
cyp11a1.2
sh565/sh565
testis
amh
expression decreased amount, abnormal
testis
dmrt1
expression decreased amount, abnormal
testis
igf3
expression decreased amount, abnormal
testis
inha
expression decreased amount, abnormal
testis
insl3
expression decreased amount, abnormal
testis
sox9a
expression decreased amount, abnormal
Fig. 8
cyp11a1.2
sh565/sh565
testis
cimap1b
expression decreased amount, abnormal
testis
nanos2
expression increased amount, abnormal
testis
piwil1
expression increased amount, abnormal
testis
sycp3
expression decreased amount, abnormal
Parajes
et al.
, 2013
Fig. 3
AB + MO1-cyp11a1.2
epiboly arrested, abnormal
whole organism dead, abnormal
Fig. 5
AB + MO2-cyp11a1.2
head decreased size, abnormal
pericardium edematous, abnormal
swim bladder uninflated, abnormal
yolk increased size, abnormal
Fig. 6
AB + MO2-cyp11a1.2
steroid biosynthetic process disrupted, abnormal
Fig. 7
AB + MO2-cyp11a1.2
cortisol biosynthetic process disrupted, abnormal
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