Publication	Data		Fish	Anatomy
Zhang et al., 2022	Fig. 7		WT + CRISPR1-gnptab + CRISPR2-gnptab + CRISPR3-gnptab + CRISPR4-gnptab	cranial cartilage morphology, abnormal embryonic cranial skeleton morphogenesis disrupted, abnormal pericardium edematous, abnormal post-vent region curved, abnormal
Flanagan-Steet et al., 2018	Fig. 4		WT + MO1-gnptab	ceratohyal cartilage morphology, abnormal Meckel's cartilage morphology, abnormal whole organism ab1-smad labeling decreased amount, abnormal whole organism Ab9-smad2 labeling increased amount, abnormal
	Fig. 6		WT + MO1-gnptab ,   y1Tg + MO1-gnptab	chondrocyte Ab2-cspg4 labeling increased amount, abnormal whole organism chst11 expression increased amount, abnormal whole organism chst13 expression increased amount, abnormal whole organism chst14 expression increased amount, abnormal whole organism chondroitin sulfate amount, abnormal
	Fig. 7		WT + MO1-gnptab ,   y1Tg + MO1-gnptab ,   ia15Tg; y1Tg + MO1-gnptab	ceratohyal cartilage morphology, abnormal chondrocyte Ab2-cspg4 labeling increased amount, abnormal chondrocyte nucleus mCherry expression increased amount, abnormal Meckel's cartilage morphology, abnormal
Flanagan-Steet et al., 2016	Fig. 1		WT + MO1-gnptab ,   y1Tg + MO1-gnptab	ceratohyal cartilage col2a1a expression increased amount, abnormal ceratohyal cartilage chondrocyte acana expression decreased amount, abnormal ceratohyal cartilage chondrocyte sox9a expression increased amount, abnormal cranial cartilage col2a1a expression increased amount, abnormal cranial cartilage chondrocyte acana expression decreased amount, abnormal cranial cartilage chondrocyte dcn expression decreased amount, abnormal cranial cartilage chondrocyte sox9a expression increased amount, abnormal cranial cartilage chondrocyte development process quality, abnormal head acana expression decreased amount, abnormal head col2a1a expression increased amount, abnormal head dcn expression decreased amount, abnormal head sox9a expression increased amount, abnormal Meckel's cartilage col2a1a expression increased amount, abnormal Meckel's cartilage chondrocyte acana expression decreased amount, abnormal Meckel's cartilage chondrocyte dcn expression decreased amount, abnormal Meckel's cartilage chondrocyte sox9a expression increased amount, abnormal palate col2a1a expression increased amount, abnormal palatoquadrate cartilage sox9a expression increased amount, abnormal palatoquadrate cartilage chondrocyte acana expression decreased amount, abnormal palatoquadrate cartilage chondrocyte sox9a expression increased amount, abnormal
	Fig. 2		WT + MO1-gnptab ,   b1212Tg + MO1-gnptab	branchiostegal ray col1a2 expression decreased amount, abnormal branchiostegal ray sp7 expression decreased amount, abnormal cleithrum col10a1a expression decreased amount, abnormal cleithrum sp7 expression decreased amount, abnormal dentary col10a1a expression decreased amount, abnormal dentary col1a2 expression decreased amount, abnormal dentary runx2a expression decreased amount, abnormal dentary sp7 expression decreased amount, abnormal dermatocranium col10a1a expression decreased amount, abnormal dermatocranium col1a2 expression decreased amount, abnormal dermatocranium runx2a expression decreased amount, abnormal dermatocranium ossification decreased occurrence, abnormal endochondral bone ossification decreased occurrence, abnormal entopterygoid col10a1a expression decreased amount, abnormal entopterygoid col1a2 expression decreased amount, abnormal head col10a1a expression decreased amount, abnormal head col1a2 expression decreased amount, abnormal head runx2a expression decreased amount, abnormal maxilla col10a1a expression decreased amount, abnormal maxilla runx2a expression decreased amount, abnormal maxilla sp7 expression decreased amount, abnormal opercle col10a1a expression decreased amount, abnormal osteoblast decreased amount, abnormal parasphenoid col10a1a expression decreased amount, abnormal parasphenoid sp7 expression decreased amount, abnormal
	Fig. 3		WT + MO1-gnptab	cranial skeletal system development process quality, abnormal embryonic viscerocranium morphogenesis process quality, abnormal splanchnocranium malformed, abnormal
	Fig. 4		y1Tg + MO1-gnptab ,   hu5910Tg + MO1-gnptab ,   mw29Tg + MO1-gnptab	ceratohyal cartilage chondrocyte Ab2-smad2/3 labeling increased amount, abnormal ceratohyal cartilage chondrocyte ab3-smad2 labeling increased amount, abnormal ceratohyal cartilage chondrocyte mCherry expression increased amount, abnormal chondrocyte nucleus Ab2-smad2/3 labeling increased amount, abnormal chondrocyte nucleus Ab2-smad2/3 labeling mislocalised, abnormal chondrocyte nucleus ab3-smad2 labeling increased amount, abnormal chondrocyte nucleus ab3-smad2 labeling mislocalised, abnormal Meckel's cartilage chondrocyte ab1-smad labeling decreased amount, abnormal Meckel's cartilage chondrocyte Ab11-smad labeling decreased amount, abnormal Meckel's cartilage chondrocyte Ab2-smad2/3 labeling increased amount, abnormal Meckel's cartilage chondrocyte ab3-smad2 labeling increased amount, abnormal Meckel's cartilage chondrocyte EGFP expression decreased amount, abnormal Meckel's cartilage chondrocyte mCherry expression increased amount, abnormal palatoquadrate cartilage chondrocyte ab1-smad labeling decreased amount, abnormal palatoquadrate cartilage chondrocyte Ab11-smad labeling decreased amount, abnormal palatoquadrate cartilage chondrocyte EGFP expression decreased amount, abnormal
	Fig. 5		WT + MO1-gnptab ,   y1Tg + MO1-gnptab ,   hu5910Tg + MO1-gnptab ,   mw29Tg + MO1-gnptab	ceratohyal cartilage chondrocyte ab3-smad2 labeling decreased amount, abnormal ceratohyal cartilage chondrocyte mCherry expression increased amount, abnormal chondrocyte nucleus ab3-smad2 labeling increased amount, abnormal chondrocyte nucleus ab3-smad2 labeling mislocalised, abnormal cranial cartilage col2a1a expression increased amount, abnormal cranial cartilage sox9a expression increased amount, abnormal dermatocranium col10a1a expression decreased amount, abnormal Meckel's cartilage chondrocyte ab1-smad labeling decreased amount, abnormal Meckel's cartilage chondrocyte ab3-smad2 labeling increased amount, abnormal Meckel's cartilage chondrocyte EGFP expression decreased amount, abnormal Meckel's cartilage chondrocyte mCherry expression increased amount, abnormal palatoquadrate cartilage chondrocyte ab1-smad labeling decreased amount, abnormal palatoquadrate cartilage chondrocyte EGFP expression decreased amount, abnormal
	Fig. 6		y1Tg + MO1-gnptab	chondrocyte extracellular space ab1-ctsk labeling mislocalised, abnormal
Flanagan-Steet et al., 2016	Fig. 1		WT + MO1-gnptab	transferase activity, transferring phosphorus-containing groups decreased process quality, abnormal
	Fig. 3		y1Tg + MO1-gnptab	ceratohyal cartilage chondrocyte disorganized, abnormal ceratohyal cartilage Collagen increased amount, abnormal Meckel's cartilage chondrocyte disorganized, abnormal Meckel's cartilage Collagen increased amount, abnormal
Qian et al., 2015	Fig. 6		WT + MO2-gnptab	ceratohyal cartilage increased angle to ceratohyal cartilage, abnormal mandibular arch skeleton decreased length, abnormal mandibular arch skeleton flattened, abnormal Meckel's cartilage decreased distance ceratohyal cartilage, abnormal
Qian et al., 2013	Fig. 4		WT + MO2-gnptab	cysteine-type peptidase activity decreased process quality, abnormal mandibular arch skeleton morphology, abnormal
Petrey et al., 2012	Fig. 9		y1Tg + MO2-gnptab	Meckel's cartilage collagen type II trimer increased amount, abnormal neurocranial trabecula collagen type II trimer increased amount, abnormal
Flanagan-Steet et al., 2009	Fig. 1		WT + MO1-gnptab ,   WT + MO2-gnptab	neurocranium blunt, abnormal pericardium edematous, abnormal ventral mandibular arch retracted, abnormal whole organism lacks parts or has fewer parts of type pectoral fin, abnormal yolk increased size, abnormal
	Fig. 2		WT + MO1-gnptab ,   y1Tg + MO1-gnptab ,   y1Tg + MO2-gnptab ,   WT + MO2-gnptab	branchiostegal ray chondrocyte spheroid, abnormal branchiostegal ray disorganized, abnormal ceratohyal cartilage malformed, abnormal inner ear morphology, abnormal palatoquadrate cartilage decreased length, abnormal
	Fig. 4		y1Tg + MO1-gnptab ,   y1Tg + MO2-gnptab	cranial cartilage collagen type II trimer increased amount, abnormal
	Fig. 5		y1Tg + MO1-gnptab ,   y1Tg + MO2-gnptab	chondrocyte intercalation involved in growth plate cartilage morphogenesis disrupted, abnormal cranial cartilage chondrocyte increased size, abnormal
	Fig. 6		WT + MO1-gnptab ,   WT + MO2-gnptab	cranial cartilage chondrocyte hyperplastic, abnormal
	Fig. 7		WT + MO1-gnptab ,   WT + MO2-gnptab	otolith decreased size, abnormal otolith mineralization disrupted, abnormal pericardium edematous, abnormal ventral mandibular arch malformed, abnormal
	Fig. 8		WT + MO1-gnptab ,   WT + MO2-gnptab	peptidyl-serine phosphorylation increased occurrence, abnormal