Fig. 1

Figure 1. DNA methylation reprogramming during sex determination and transition in zebrafish Sex determination and plasticity are regulated by epigenetic mechanisms in zebrafish. DNA methylation is crucial for sex determination in the larval stage (on the top). 5-Aza treatment can reduce the sex transition induced by Aromasin, suggesting that DNA methylation dynamics plays an essential role in sex reversal in the adult stage (at the bottom). PGC, primordial germ cell; FGC, female germ cell; MGC, male germ cell; dpf, day post fertilization.

Acknowledgments
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