Corral-Serrano et al., 2018 - C2orf71a/pcare1 is important for photoreceptor outer segment morphogenesis and visual function in zebrafish. Scientific Reports   8:9675 Full text @ Sci. Rep.

Fig. 3

Pcare1rmc100/rmc100 zebrafish show aberrant photoreceptor morphology. (A) Analysis of the morphology of the pcare1rmc100/rmc100 zebrafish larval retina (5 dpf) using boron-dipyrromethene (BODIPY) revealed disorganization of photoreceptor outer segments as compared to those of strain- and age-matched wild-type larvae (arrows). (B) Siblings of adult zebrafish without (wild-type) or containing (pcare1rmc100/rmc100) the 29 bp deletion in pcare1 were sectioned and stained with antibodies against F-actin (red), Rhodopsin (green) or, in (C) GNAT2 (green). Arrows indicate normal outer segments in control fish and dysmorphic outer segments in mutant fish. Nuclei were stained with DAPI.

ZFIN wishes to thank the journal Scientific Reports for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Sci. Rep.