Genomic Feature
hi2578Tg
- ID
- ZDB-ALT-041007-14
- Name
- hi2578Tg
- Synonyms
-
- hi2578 (1)
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- embryos treated with DNA
- Lab of Origin
- Hopkins Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
Comment | Citation |
---|---|
The construct was inserted on the minus strand of the genome. The gene in which ... | ZFIN Curated Data |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 7: 1505794 - 1505795 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- Insertion in Intron 1 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
---|---|---|---|---|---|
nop10hi2578Tg/hi2578Tg | Homozygous | Unknown | 6 figures from 2 publications | 3 figures from Pereboom et al., 2011 | |
nop10hi2578Tg/+ (AB) | Heterozygous | Unknown | |||
nop10hi2578Tg/+ (AB/TU) | Heterozygous | Unknown | |||
nop10hi2578Tg | Unknown | Unknown | Fig. for (hi2578) ![]() | Fig. 1 from Pereboom et al., 2011 | |
nop10hi2578Tg; rps7hi1034bTg | Complex | Fig. 4 from Pereboom et al., 2011 | |||
tp53zdf1; nop10hi2578Tg | Complex | Fig. 5 from Pereboom et al., 2011 | Fig. 5 from Pereboom et al., 2011 |
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Supplemental Information
- Genotyping protocol
- None
- Pereboom, T.C., Weele, L.J., Bondt, A., and Macinnes, A.W. (2011) A zebrafish model of dyskeratosis congenita reveals hematopoetic stem cell formation failure due to ribosomal protein-mediated p53 stabilization. Blood. 118(20):5458-65
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
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