Genomic Feature
hi2939Tg
- ID
- ZDB-ALT-040824-16
- Name
- hi2939Tg
- Synonyms
-
- hi2939 (1)
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- DNA
- Lab of Origin
- Hopkins Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
| Comment | Citation |
|---|---|
| The construct was inserted on the plus strand of the genome. The gene in which ... | ZFIN Curated Data |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 13: 1150988 - 1150989 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- Insertion in Intron 1 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| psmb1hi2939Tg/hi2939Tg | Homozygous | Unknown | 2 figures  from Weeks et al., 2022 | 2 figures from Weeks et al., 2022 | |
| psmb1hi2939Tg/hi2939Tg | Homozygous | ♀+/- ♂+/- | 6 figures from 2 publications | 3 figures from Miller et al., 2024 | |
| psmb1hi2939Tg/+ (AB) | Heterozygous | Unknown | |||
| psmb1hi2939Tg/+ (AB/TU) | Heterozygous | Unknown | |||
| psmb1hi2939Tg | Unknown | Unknown | Fig. for (hi2939) from Phenotype Annotation (1994-2006) | ||
| psmb1hi2939Tg/hi2939Tg; s854Tg | Complex | Figure 3 from Miller et al., 2024 | |||
| psmb1hi2939Tg/hi2939Tg; y1Tg | Complex | Figure 3 from Miller et al., 2024 | |||
| psmb1hi2939Tg/hi2939Tg; zf393Tg | Complex | 3 figures from Miller et al., 2024 | |||
| psmb1hi2939Tg/hi2939Tg; zf393Tg; zf4006Tg | Complex | Figure 6 from Miller et al., 2024 | |||
| psmb1hi2939Tg/hi2939Tg; zf4006Tg | Complex | Figure 6 from Miller et al., 2024 |
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Supplemental Information
- Genotyping protocol
- None
- Miller, B.M., Goessling, W. (2024) The proteasome subunit psmb1 is essential for craniofacial cartilage maturation and morphogenesis. JCI insight. 9(16):
- Weeks, O., Miller, B.M., Pepe-Mooney, B.J., Oderberg, I.M., Freeburg, S.H., Smith, C.J., North, T.E., Goessling, W. (2022) Embryonic alcohol exposure disrupts the ubiquitin-proteasome system. JCI insight. 7(23):
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
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