Genomic Feature
hi3112aTg
- ID
- ZDB-ALT-040220-8
- Name
- hi3112aTg
- Synonyms
-
- hi3112a (1)
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- embryos treated with DNA
- Lab of Origin
- Hopkins Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
| Comment | Citation |
|---|---|
| The construct was inserted on the plus strand of the genome. The gene in which ... | ZFIN Curated Data |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 17: 19481915 - 19481916 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- Insertion in Intron 2 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| kif11hi3112aTg/hi3112aTg | Homozygous | Unknown | 4 figures  from Johnson et al., 2014 | ||
| kif11hi3112aTg/hi3112aTg (AB/TU) | Homozygous | ♀+/- ♂+/- | 2 figures from Barresi et al., 2010 | Fig. 3 from Barresi et al., 2010 | |
| kif11hi3112aTg/+ (AB) | Heterozygous | Unknown | |||
| kif11hi3112aTg/+ (AB/TU) | Heterozygous | Unknown | |||
| kif11hi3112aTg | Unknown | Unknown | Fig. for (hi3112a) from Phenotype Annotation (1994-2006) | ||
| kif11hi3112aTg (AB/TU) | Unknown | Unknown |
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Supplemental Information
- Genotyping protocol
- hi3112atg.pdf
- Johnson, K., Moriarty, C., Tania, N., Ortman, A., Dipietrantonio, K., Edens, B., Eisenman, J., Ok, D., Krikorian, S., Barragan, J., Golé, C., and Barresi, M.J. (2014) Kif11 dependent cell cycle progression in radial glial cells is required for proper neurogenesis in the zebrafish neural tube. Developmental Biology. 387(1):73-92
- Barresi, M.J., Burton, S., Dipietrantonio, K., Amsterdam, A., Hopkins, N., and Karlstrom, R.O. (2010) Essential genes for astroglial development and axon pathfinding during zebrafish embryogenesis. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(10):2603-2618
- Golling, G., Amsterdam, A., Sun, Z., Antonelli, M., Maldonado, E., Chen, W., Burgess, S., Haldi, M., Artzt, K., Farrington, S., Lin, S.Y., Nissen, R.M., and Hopkins, N. (2002) Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Nature Genetics. 31(2):135-140
- Amsterdam, A., Burgess, S., Golling, G., Chen, W., Sun, Z., Townsend, K., Farrington, S., Haldi, M., and Hopkins, N. (1999) A large-scale insertional mutagenesis screen in zebrafish. Genes & Development. 13(20):2713-2724
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