ZFIN ID: ZDB-EXP-220429-13 |
Experiment Conditions Description: chemical treatment by environment: SB 431542, chemical treatment by environment: insulin
chemical treatment by environment: SB 431542 |
---|
Name: | chemical treatment by environment |
---|---|
Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | SB 431542 |
---|---|
Synonyms: | 4-(4-(1,3-Benzodioxole-5-yl)-5-(2-pyridyl)-1H-imidazole-2-yl)benzamide, 4-[4-(2H-1,3-benzodioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl]benzamide, SB-431542, SB431542 |
Definition: | A member of the class of benzamides that is 4-(imidazol-2-yl)benzamide carrying additional 1,3-benzodioxol-5-yl and pyridin-2-yl substituents at positions 4 and 5 respectively on the imidazole ring. |
Ontology: | ChEBI [CHEBI:91108] ( EBI ) |
chemical treatment by environment: insulin |
---|
Name: | chemical treatment by environment |
---|---|
Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | insulin |
---|---|
Synonyms: | |
Definition: | A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the beta cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies. |
Ontology: | ChEBI [CHEBI:145810] ( EBI ) |
Publication: | Budi et al., 2019 |
---|