| ZFIN ID: ZDB-EXP-211102-5 |
Experiment Conditions Description: chemical treatment by environment: crizotinib
| chemical treatment by environment: crizotinib |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | crizotinib |
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| Synonyms: | (R)-crizotinib, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine, crizotinib, crizotinibum, PF 2341066, PF-2341066 |
| Definition: | A 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has R configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) |
| Ontology: | ChEBI [CHEBI:64310] ( EBI ) |
| Publication: | Isabella et al., 2020 |
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