ZFIN ID: ZDB-EXP-210429-5
Experiment Conditions Description: chemical ablation: osteoblast, chemical treatment by environment: nifurpirinol, chemical treatment by environment: prednisolone
chemical ablation: osteoblast
Name: chemical ablation
Synonyms:
Definition: Experimental condition which uses a chemical to ablate an anatomical structure or cell.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000169]
Name: osteoblast
Synonyms: osteoblasts
Definition: A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
Ontology: Anatomy Ontology [ZFA:0009031]
chemical treatment by environment: nifurpirinol
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: nifurpirinol
Synonyms: furanace, furpirinol, furpyrinol, prefuran
Definition:
Ontology: ChEBI [CHEBI:135000]  ( EBI )
chemical treatment by environment: prednisolone
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: prednisolone
Synonyms: (11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione, 1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione, 1,4-pregnadiene-3,20-dione-11beta,17alpha,21-triol, 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione, 3,20-dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene, Delta(1)-dehydrocortisol, Delta(1)-dehydrohydrocortisone, Delta(1)-hydrocortisone, hydroretrocortine, metacortandralone, prednisolona, prednisolone, prednisolonum
Definition: A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Ontology: ChEBI [CHEBI:8378]  ( EBI )
Publication: McDonald et al., 2021