| ZFIN ID: ZDB-EXP-201103-11 |
Experiment Conditions Description: chemical treatment by environment: oxidopamine, chemical treatment by environment: nabumetone
| chemical treatment by environment: oxidopamine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | oxidopamine |
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| Synonyms: | 2,4,5-trihydroxyphenethylamine, 5-(2-aminoethyl)benzene-1,2,4-triol, 6-hydroxydopamine, 6-OHDA, hydroxydopamine, oxidopamina, oxidopamine, oxidopaminum, topamine |
| Definition: | A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). |
| Ontology: | ChEBI [CHEBI:78741] ( EBI ) |
| chemical treatment by environment: nabumetone |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | nabumetone |
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| Synonyms: | 4-(6-Methoxy-2-naphthalenyl)-2-butanone, 4-(6-Methoxy-2-naphthyl)-2-butanone, nabumetona, nabumetone, nabumetonum, Relafen |
| Definition: | A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs. |
| Ontology: | ChEBI [CHEBI:7443] ( EBI ) |
| Publication: | Vaz et al., 2019 |
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