ZFIN ID: ZDB-EXP-201102-4
Experiment Conditions Description: chemical treatment by environment: fingolimod
chemical treatment by environment: fingolimod
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: fingolimod
Synonyms: 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol, fingolimod, fingolimodum, FTY720
Definition: An aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimod is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate.
Ontology: ChEBI [CHEBI:63115]  ( EBI )
Publication: Vicente et al., 2019