| ZFIN ID: ZDB-EXP-190924-8 |
Experiment Conditions Description: chemical treatment by environment: IWR-1-endo, chemical treatment by environment: NSC 23766 trihydrochloride
| chemical treatment by environment: IWR-1-endo |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | IWR-1-endo |
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| Synonyms: | 4-[(3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, IRW1 |
| Definition: | A dicarboximide having an endo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. |
| Ontology: | ChEBI [CHEBI:62882] ( EBI ) |
| chemical treatment by environment: NSC 23766 trihydrochloride |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | NSC 23766 trihydrochloride |
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| Synonyms: | N(6)-(2-{[5-(diethylamino)pentan-2-yl]amino}-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride, NSC 23766.3HCl, NSC-23766.3HCl, NSC23766.3HCl |
| Definition: | A hydrochloride resulting from the formal reaction of NSC 23766 with 3 mol eq. of hydrogen chloride. An inhibitor of the signalling G-protein known as RAC1 (Ras-related C3 botulinum toxin substrate 1). |
| Ontology: | ChEBI [CHEBI:144949] ( EBI ) |
| Publication: | Hübner et al., 2018 |
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