ZFIN ID: ZDB-EXP-190401-1
Experiment Conditions Description: chemical treatment by injection: PDGF receptor tyrosine kinase inhibitor III, resection: cardiac ventricle
chemical treatment by injection: PDGF receptor tyrosine kinase inhibitor III
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: PDGF receptor tyrosine kinase inhibitor III
Synonyms: 4-(6,7-dimethoxyquinazolin-4-yl)-N-(4-phenoxyphenyl)piperazine-1-carboxamide, N-(4-phenoxyphenyl)-4-(6,7-dimethoxyquinazoline-4-yl)piperazine-1-carboxamide, PDGFR tyrosine kinase inhibitor III
Definition: An N-arylpiperazine that is piperazine in which the hydrogen attached to the nitrogen at position 1 is replaced by a (4-phenoxyphenyl)aminocarbonyl group, while the hydrogen attached to the nitrogen at position 4 is replaced by a 6,7-dimethoxyquinazolin-4-yl group. It is an inhibitor of tyrosine kinases FLT3, PDGFR and KIT.
Ontology: ChEBI [CHEBI:143127]  ( EBI )
resection: cardiac ventricle
Name: resection
Synonyms:
Definition: Surgical manipulation in which a particular organ, appendage, or part of an organism is removed.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000171]
Name: cardiac ventricle
Synonyms: ventricle
Definition: Cavitated compound organ that receives blood flow from the atrium and delivers blood to the body via the aorta. Valves are present to direct flow. There are only two chambers present in the fish heart.
Ontology: Anatomy Ontology [ZFA:0000009]
Publication: Missinato et al., 2018