| ZFIN ID: ZDB-EXP-181205-7 |
Experiment Conditions Description: chemical treatment by environment: dactolisib
| chemical treatment by environment: dactolisib |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | dactolisib |
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| Synonyms: | 2-methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile, BEZ 235, BEZ-235, BEZ235, NVP BEZ235, NVP-BEZ 235, NVP-BEZ235, NVPBEZ235 |
| Definition: | An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 4-(1-cyanoisopropyl)phenyl group and at position 8 by a quinolin-3-yl group. A dual PI3K/mTOR inhibitor used in cancer treatment. |
| Ontology: | ChEBI [CHEBI:71952] ( EBI ) |
| Publication: | Li et al., 2018 |
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