| ZFIN ID: ZDB-EXP-180926-3 |
Experiment Conditions Description: chemical treatment by injection: dizocilpine, physical alteration: brain
| chemical treatment by injection: dizocilpine |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | dizocilpine |
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| Synonyms: | (+)-dizocilpine, (+)-MK-801, (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, dizocilpina, dizocilpine, dizocilpinum, MK 801, MK-801, MK801 |
| Definition: | An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory. |
| Ontology: | ChEBI [CHEBI:34725] ( EBI ) |
| physical alteration: brain |
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| Name: | physical alteration |
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| Synonyms: | |
| Definition: | Experimental condition in which an anatomical structure, cell, or organ has sustained targeted physical change, usually through the use of an instrument. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000229] |
| Name: | brain |
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| Synonyms: | brain structure |
| Definition: | Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system. |
| Ontology: | Anatomy Ontology [ZFA:0000008] |
| Publication: | McCutcheon et al., 2017 |
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