| ZFIN ID: ZDB-EXP-180307-5 |
Experiment Conditions Description: high cholesterol, chemical treatment by diet: probucol
| high cholesterol |
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| Name: | high cholesterol |
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| Synonyms: | |
| Definition: | Cholesterol content condition in which the amount of cholesterol in the diet is elevated. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000119] |
| chemical treatment by diet: probucol |
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| Name: | chemical treatment by diet |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the diet. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000239] |
| Name: | probucol |
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| Synonyms: | 4,4'- (Isopropylidenedithio)bis(2,6-di-tert-butylphenol), 4,4'-(propane-2,2-diyldisulfanediyl)bis(2,6-di-tert-butylphenol), Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole, Biphenabid, Bisbid, Bisphenabid, DH-581, Lesterol, Lorelco, Lurselle, probucol, probucolum, Serterol, Superlipid |
| Definition: | A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood. |
| Ontology: | ChEBI [CHEBI:8427] ( EBI ) |
| Publication: | Liu et al., 2017 |
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