| ZFIN ID: ZDB-EXP-180220-6 |
Experiment Conditions Description: chemical treatment by injection: ouabain, chemical treatment by environment: methionine, chemical ablation: retinal ganglion cell
| chemical treatment by injection: ouabain |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | ouabain |
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| Synonyms: | 3-(6-deoxy-alpha-L-mannopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide, 3-(alpha-L-rhamnopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide, G-Strophanthin, Ouabagenin L-Rhamnoside, Ouabagenin-L-rhamnosid, Ouabain, Ouabain anhydrous, Ouabaine, Oubain, Strodival |
| Definition: | A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus. |
| Ontology: | ChEBI [CHEBI:472805] ( EBI ) |
| chemical treatment by environment: methionine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | methionine |
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| Synonyms: | 2-amino-4-(methylsulfanyl)butanoic acid, 2-amino-4-(methylthio)butanoic acid, 2-Amino-4-(methylthio)butyric acid, alpha-amino-gamma-methylmercaptobutyric acid, DL-Methionine, Hmet, M, Met, Methionin, Methionine, metionina, Racemethionine |
| Definition: | A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. |
| Ontology: | ChEBI [CHEBI:16811] ( EBI ) |
| chemical ablation: retinal ganglion cell |
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| Name: | chemical ablation |
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| Synonyms: | |
| Definition: | Experimental condition which uses a chemical to ablate an anatomical structure or cell. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000169] |
| Name: | retinal ganglion cell |
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| Synonyms: | gangliocyte, RGC |
| Definition: | The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. |
| Ontology: | Anatomy Ontology [ZFA:0009310] |
| Publication: | Li et al., 2017 |
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