| ZFIN ID: ZDB-EXP-170613-6 |
Experiment Conditions Description: bacterial treatment by injection: Mycobacteroides abscessus, chemical treatment by environment: avibactam, chemical treatment by environment: imipenem
| bacterial treatment by injection: Mycobacteroides abscessus |
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| Name: | bacterial treatment by injection |
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| Synonyms: | |
| Definition: | Bacterial treatment where the bacteria are injected into the fish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000230] |
| Name: | Mycobacteroides abscessus |
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| Synonyms: | "Mycobacterium abcessus" Moore and Frerichs 1953, "Mycobacterium chelonei" (sic) Bergey et al. 1923, Mycobacterium abscessus, Mycobacterium chelonae subsp. abscessus, Mycobacterium chelonei subsp. abscessus |
| Definition: | |
| Ontology: | Taxonomy for ZECO [NCBITaxon:36809] |
| chemical treatment by environment: avibactam |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | avibactam |
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| Synonyms: | (2S,5R)-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide, NXL 104, NXL104 |
| Definition: | A member of the class of azabicycloalkanes that is (2S,5R)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide in which the amino hydrogen at position 6 is replaced by a sulfooxy group. Used (in the form of its sodium salt) in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. |
| Ontology: | ChEBI [CHEBI:85984] ( EBI ) |
| chemical treatment by environment: imipenem |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | imipenem |
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| Synonyms: | (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure, (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, Imipenem, Imipenem anhydrous, imipenemum, N-formimidoyl thienamycin, N-formimidoylthienamycin |
| Definition: | A broad-spectrum, intravenous beta-lactam antibiotic of the carbapenem subgroup. |
| Ontology: | ChEBI [CHEBI:471744] ( EBI ) |
| Publication: | Lefebvre et al., 2017 |
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