ZFIN ID: ZDB-EXP-170530-6
Experiment Conditions Description: cancer xenotransplantation, chemical treatment by environment: trametinib, chemical treatment by environment: sunitinib
cancer xenotransplantation
Name: cancer xenotransplantation
Synonyms:
Definition: Xenotransplantation condition in which cancer cells are injected or grafted into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000236]
chemical treatment by environment: trametinib
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: trametinib
Synonyms: GSK 1120212, JTP 74057, N-(3-{3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl}phenyl)acetamide, trametinib, trametinibum
Definition: A pyridopyrimidine that is used (as its dimethyl sulfoxide addition compound) for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment.
Ontology: ChEBI [CHEBI:75998]  ( EBI )
chemical treatment by environment: sunitinib
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: sunitinib
Synonyms: N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide, SU-11248, Sunitinib, sunitinibum, Sutent
Definition:
Ontology: ChEBI [CHEBI:38940]  ( EBI )
Publication: Ki et al., 2017