| ZFIN ID: ZDB-EXP-161027-4 |
Experiment Conditions Description: chemical treatment: mycophenolic acid, chemical treatment: methionine sulfoximine
| chemical treatment: mycophenolic acid |
|---|
| Name: | chemical treatment |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | mycophenolic acid |
|---|---|
| Synonyms: | (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid, (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid, acide mycophenolique, acido micofenolico, acidum mycophenolicum, Micofenolico acido, Mycophenolate, mycophenolic acid, Mycophenolsaeure |
| Definition: | A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases. |
| Ontology: | ChEBI [CHEBI:168396] ( EBI ) |
| chemical treatment: methionine sulfoximine |
|---|
| Name: | chemical treatment |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | methionine sulfoximine |
|---|---|
| Synonyms: | 2-amino-4-(S-methylsulfonimidoyl)butanoic acid, 2-amino-4-(S-methylsulphonimidoyl)butyric acid, Methionine sulfoximine |
| Definition: | A non-proteinogenic alpha-amino acid that is the sulfoximine derivative of methionine . |
| Ontology: | ChEBI [CHEBI:47833] ( EBI ) |
| Publication: | Cox et al., 2016 |
|---|