| ZFIN ID: ZDB-EXP-160129-13 |
Experiment Conditions Description: heat exposure, amputation: caudal fin, chemical treatment: tacrolimus hydrate
| heat exposure |
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| Name: | heat exposure |
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| Synonyms: | |
| Definition: | Temperature exposure condition in which fish are raised in temperature that is higher than the controlled temperature. The standard controlled temperature (according to the zebrafish book) is 28.5 degrees C. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000163] |
| amputation: caudal fin |
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| Name: | amputation |
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| Synonyms: | |
| Definition: | Resection condtion in which all or part of an extremity such as the fin or tail are removed. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000172] |
| Name: | caudal fin |
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| Synonyms: | tail, tail fin |
| Definition: | Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines. |
| Ontology: | Anatomy Ontology [ZFA:0001058] |
| chemical treatment: tacrolimus hydrate |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | tacrolimus hydrate |
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| Synonyms: | (-)-(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-1, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19, Prograf, Protopic, tacrolimus, tacrolimus monohydrate, tsukubaenolide hydrate |
| Definition: | A hydrate that is the monohydrate form of tacrolimus. |
| Ontology: | ChEBI [CHEBI:61057] ( EBI ) |
| Publication: | Chen et al., 2015 |
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