| ZFIN ID: ZDB-EXP-150212-3 |
Experiment Conditions Description: ablation: posterior lateral line nerve, chemical treatment: tyrphostin AG 1478
| ablation: posterior lateral line nerve |
|---|
| Name: | ablation |
|---|---|
| Synonyms: | |
| Definition: | Targeted destruction of an anatomical structure. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000168] |
| Name: | posterior lateral line nerve |
|---|---|
| Synonyms: | caudal lateral line nerve |
| Definition: | Cranial nerve which enters the brain between cranial nerves VIII and IX; contains afferents and sensory efferents to the posterior lateral line ganglion and middle ganglion. Fibers from the posterior lateral line ganglion innervate the occipital dorsal lateral line and trunk lateral lines. |
| Ontology: | Anatomy Ontology [ZFA:0000175] |
| chemical treatment: tyrphostin AG 1478 |
|---|
| Name: | chemical treatment |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | tyrphostin AG 1478 |
|---|---|
| Synonyms: | AG 1478, AG-1478, N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine, tyrphostin AG-1478 |
| Definition: | A member of the class of quinazolines that is quinazoline substituted by methoxy groups at positions 6 and 7 and a (3-chlorophenyl)nitrilo group at position 4. It acts as an epidermal growth factor receptor antagonist. |
| Ontology: | ChEBI [CHEBI:75404] ( EBI ) |
| Publication: | Ceci et al., 2014 |
|---|