| ZFIN ID: ZDB-EXP-260812-5 |
Experiment Conditions Description: chemical treatment by environment: monomethyl fumarate
| chemical treatment by environment: monomethyl fumarate |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | monomethyl fumarate |
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| Synonyms: | (2E)-4-methoxy-4-oxobut-2-enoic acid, (E)-4-methoxy-4-oxobut-2-enoic acid, Bafiertam, fumarate de monomethyle, fumarato de monometilo, fumaric acid monomethyl ester, methyl hydrogen fumarate, mono-methyl fumarate, monomethyl fumarate, monomethylfumarate, monomethylis fumaras |
| Definition: | A dicarboxylic acid monoester resulting from the formal condensation of one of the carboxy groups of fumaric acid with methanol. Is is a metabolite of dimethyl fumarate and used for the the treatment of patients with relapsing multiple sclerosis (MS). It also induces the NFE2L2 (Nrf2) transcription factor by binding to KEAP1. |
| Ontology: | ChEBI [CHEBI:167450] ( EBI ) |
| Publication: | Zhang et al., 2023 |
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