ZFIN ID: ZDB-EXP-250703-3
Experiment Conditions Description: heat shock, chemical treatment by environment: antalarmin
heat shock
Name: heat shock
Synonyms:
Definition: Temperature shock condition in which fish are subjected for a short period of time to temperature higher than the controlled temperature. The standard controlled temperature (according to the zebrafish book) is 28.5 degrees C.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000166]
chemical treatment by environment: antalarmin
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: antalarmin
Synonyms: N-butyl-N-ethyl-7-mesityl-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Definition: A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidin-4-amine which is substituted by methyl groups at positions 2, 5, and 6, by a mesityl group at position 7, and in which the amino substituent at position 4 has been substituted by ethyl and butyl groups. It is an antagonist of corticotropin-releasing factor 1 (CRF-1) receptors (Ki = 1 nM).
Ontology: ChEBI [CHEBI:139557]  ( EBI )
Publication: Rajeswari et al., 2025