| ZFIN ID: ZDB-EXP-250611-6 |
Experiment Conditions Description: chemical treatment by environment: ofloxacin
| chemical treatment by environment: ofloxacin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | ofloxacin |
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| Synonyms: | (+-)-ofloxacin, (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, DL 8280, DL-8280, Exocin, Floxin, Gailuoxian, HOE 280, HOE-280, Ocuflox, ofloxacin, ofloxacine, ofloxacino, ofloxacinum, OFLX, ORF 18489, Oxaldin, Prifloxcin, Prifloxin, rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid, rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, rac-ofloxacin, racemic ofloxacin, Tarivid, Visiren |
| Definition: | A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. |
| Ontology: | ChEBI [CHEBI:7731] ( EBI ) |
| Publication: | Geng et al., 2022 |
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