| ZFIN ID: ZDB-EXP-220123-5 |
Experiment Conditions Description: chemical treatment by environment: methoxsalen, chemical treatment by environment: oxidopamine
| chemical treatment by environment: methoxsalen |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | methoxsalen |
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| Synonyms: | 6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone, 8-methoxy-2',3',6,7-furocoumarin, 8-methoxy-4',5':6,7-furocoumarin, 8-methoxy-[furano-3'.2':6.7-coumarin], 8-Methoxyfuranocoumarin, 8-Methoxypsoralen, 8-MOP, 8-MP, 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one, 9-methoxy-7H-furo[3,2-g]chromen-7-one, Meladinine, Meloxine, Methoxsalen, O-Methylxanthotoxol, Oxsoralen, Ultra Mop, Uvadex, xanthotoxin |
| Definition: | A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis. |
| Ontology: | ChEBI [CHEBI:18358] ( EBI ) |
| chemical treatment by environment: oxidopamine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | oxidopamine |
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| Synonyms: | 2,4,5-trihydroxyphenethylamine, 5-(2-aminoethyl)benzene-1,2,4-triol, 6-hydroxydopamine, 6-OHDA, hydroxydopamine, oxidopamina, oxidopamine, oxidopaminum, topamine |
| Definition: | A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). |
| Ontology: | ChEBI [CHEBI:78741] ( EBI ) |
| Publication: | KozioĊ et al., 2020 |
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