| ZFIN ID: ZDB-EXP-210803-3 |
Experiment Conditions Description: chemical treatment by injection: myriocin
| chemical treatment by injection: myriocin |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | myriocin |
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| Synonyms: | (2S,3R,4R)-(E)-2-amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic acid, (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid, (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid, antibiotic ISP-1, antibiotic ISP-I, ISP-1, ISP-I, thermozymocidin |
| Definition: | An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity. |
| Ontology: | ChEBI [CHEBI:582124] ( EBI ) |
| Publication: | Castanon et al., 2020 |
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