| ZFIN ID: ZDB-EXP-191029-5 |
Experiment Conditions Description: chemical treatment by injection: trehalose 6,6'-dimycolate, chemical treatment by environment: pazopanib
| chemical treatment by injection: trehalose 6,6'-dimycolate |
|---|
| Name: | chemical treatment by injection |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | trehalose 6,6'-dimycolate |
|---|---|
| Synonyms: | 6-O-{3-hydroxy-2-[10-(2-octadecylcyclopropyl)decyl]octacosanoyl}-alpha-D-glucopyranosyl 6-O-{3-hydroxy-2-[10-(2-octadecylcyclopropyl)decyl]octacosanoyl}-alpha-D-glucopyranoside, AC1L9PSR, alpha,alpha'-trehalose 6,6'-dimycolate, cord factor, mycobacterial trehalose dimycolate, trehalose dimycolate |
| Definition: | A trehalose mycolate compound consisting of two C58 mycolate groups attached to the 6- and 6'-positions of alpha,alpha'-trehalose. A mycobacterial cell wall glycolipid. |
| Ontology: | ChEBI [CHEBI:82624] ( EBI ) |
| chemical treatment by environment: pazopanib |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | pazopanib |
|---|---|
| Synonyms: | 5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide, GW 78603, GW786034, pazopanib, pazopanibum |
| Definition: | A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer. |
| Ontology: | ChEBI [CHEBI:71219] ( EBI ) |
| Publication: | Walton et al., 2018 |
|---|