TALEN

TALEN1-hsf4

ID

ZDB-TALEN-180319-1

Name

TALEN1-hsf4

Previous Names

None

Target

hsf4 (1)

Target Sequence 1

5' - AGCAATGTGCCCGCTTT - 3'

Target Sequence 2

5' - CCGGGTCCTCGACCAGAGT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hzu5	hsf4

Expression

Gene expression in Wild Types + TALEN1-hsf4

No data available

Phenotype

Phenotype resulting from TALEN1-hsf4

No data available

Phenotype of all Fish created by or utilizing TALEN1-hsf4

Phenotype	Fish	Conditions	Figures
lens il15 expression increased amount, abnormal	hsf4^hzu5/hzu5	standard conditions	Fig. 7 from Cui et al., 2021
maintenance of lens transparency disrupted, abnormal	hsf4^hzu5/hzu5	standard conditions	Fig. 6 from Cui et al., 2019
lens cxcl12a expression increased amount, abnormal	hsf4^hzu5/hzu5	standard conditions	Fig. 7 from Cui et al., 2021
lens mif expression increased amount, abnormal	hsf4^hzu5/hzu5	standard conditions	Fig. 7 from Cui et al., 2021
lens epithelium senescent, abnormal	hsf4^hzu5/hzu5	standard conditions	Fig. 7 from Cui et al., 2021
lens cdkn1a expression increased amount, abnormal	hsf4^hzu5/hzu5	standard conditions	Fig. 7 from Cui et al., 2021
lens cryaba expression decreased amount, abnormal	hsf4^hzu5/hzu5	standard conditions	Fig. 6 from Cui et al., 2019
lens epithelium cellular senescence increased process quality, abnormal	hsf4^hzu5/hzu5	standard conditions	Fig. 7 from Cui et al., 2021
lens opaque, abnormal	hsf4^hzu5/hzu5	standard conditions	Fig. 7 from Cui et al., 2021
lens tp53 expression decreased amount, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 7 from Gao et al., 2017
whole organism hsf4 expression absent, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 1 from Gao et al., 2017
lens opaque, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 2 from Gao et al., 2017
activation of cysteine-type endopeptidase activity involved in apoptotic process decreased process quality, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 7 from Gao et al., 2017
lens enucleation decreased process quality, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 5, Fig. 6 from Zhang et al., 2020
lens fiber cell differentiation process quality, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 5, Fig. 6 from Zhang et al., 2020
lens dnase1l1l expression absent, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 5 from Zhang et al., 2020
lens epithelium epithelial cell increased amount, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. S2 from Gao et al., 2017
lens fiber cell late endosome mislocalised, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 3 from Gao et al., 2017
lens fiber cell early endosome present, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 3 from Gao et al., 2017
lens fiber cell disorganized, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 4 from Gao et al., 2017
lens fiber cell increased amount, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 4 from Gao et al., 2017
lens fiber cell nucleus present, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 2, Fig. 3, Fig. 7 from Gao et al., 2017
lens fiber cell organelle present, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 3 from Gao et al., 2017
lens fiber cell differentiation disrupted, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 2, Fig. 3, Fig. 7 from Gao et al., 2017
lens fiber cell late endosome present, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 3 from Gao et al., 2017
lens nucleated, abnormal	hsf4^hzu5/hzu5 (AB)	standard conditions	Fig. 5, Fig. 6 from Zhang et al., 2020

Citations