TALEN

TALEN1-pkd1a

ID

ZDB-TALEN-170524-1

Name

TALEN1-pkd1a

Previous Names

None

Target

pkd1a (1)

Target Sequence 1

5' - TACCACAACCACAGGCAG - 3'

Target Sequence 2

5' - TGCCCTGCCGAAGCAC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf1067	pkd1a
zf1068	pkd1a

Expression

Gene expression in Wild Types + TALEN1-pkd1a

No data available

Phenotype

Phenotype resulting from TALEN1-pkd1a

No data available

Phenotype of all Fish created by or utilizing TALEN1-pkd1a

Phenotype	Fish	Conditions	Figures
pronephric duct cystic, ameliorated	pkd1a^{zf1067/zf1067}	chemical treatment by environment: carbamazepine, chemical treatment by environment: sirolimus	Fig. 6 from Zhu et al., 2017
pronephric duct has fewer parts of type pronephric duct autophagosome, abnormal	pkd1a^{zf1067/zf1067}	chemical treatment by environment: bafilomycin A1	Fig. 2 from Zhu et al., 2017
pronephros renal filtration occurrence, ameliorated	pkd1a^{zf1067/zf1067}	chemical treatment by environment: bafilomycin A1	Fig. 6 from Zhu et al., 2017
pronephros renal filtration occurrence, ameliorated	pkd1a^{zf1067/zf1067}	chemical treatment by environment: sirolimus	Fig. 6 from Zhu et al., 2017
pronephros renal filtration decreased occurrence, abnormal	pkd1a^{zf1067/zf1067}	control	Fig. 1, Fig. 6 from Zhu et al., 2017
pronephros development decreased process quality, abnormal	pkd1a^{zf1067/zf1067}	standard conditions	Fig. 1, Fig. 4 from Zhu et al., 2017
pronephric duct cystic, ameliorated	pkd1a^{zf1067/zf1067}	chemical treatment by environment: sirolimus	Fig. 6 from Zhu et al., 2017
heart edematous, abnormal	pkd1a^{zf1067/zf1067}	standard conditions	Fig. 1 from Zhu et al., 2017
TOR signaling increased occurrence, abnormal	pkd1a^{zf1067/zf1067}	standard conditions	Fig. 2 from Zhu et al., 2017
pronephros renal filtration occurrence, ameliorated	pkd1a^{zf1067/zf1067}	chemical treatment by environment: minoxidil	Fig. 6 from Zhu et al., 2017
pronephric tubule dilated, abnormal	pkd1a^{zf1067/zf1067}	standard conditions	Fig. 1 from Zhu et al., 2017
pronephric duct cystic, ameliorated	pkd1a^{zf1067/zf1067}	chemical treatment by environment: bafilomycin A1	Fig. 6 from Zhu et al., 2017
pronephric duct regulation of autophagy process quality, abnormal	pkd1a^{zf1067/zf1067}	standard conditions	Fig. 2 from Zhu et al., 2017
pronephric duct cystic, ameliorated	pkd1a^{zf1067/zf1067}	chemical treatment by environment: carbamazepine	Fig. 6 from Zhu et al., 2017
whole organism Ab6-mtor labeling increased amount, abnormal	pkd1a^{zf1067/zf1067}	standard conditions	Fig. 2 from Zhu et al., 2017
pronephric duct cystic, abnormal	pkd1a^{zf1067/zf1067}	control	Fig. 1, Fig. 6 from Zhu et al., 2017
pronephros renal filtration occurrence, ameliorated	pkd1a^{zf1067/zf1067}	chemical treatment by environment: carbamazepine	Fig. 6 from Zhu et al., 2017
pronephric duct autophagy decreased occurrence, abnormal	pkd1a^{zf1067/zf1067}	chemical treatment by environment: bafilomycin A1	Fig. 2 from Zhu et al., 2017
pronephric duct cystic, ameliorated	pkd1a^{zf1067/zf1067}	chemical treatment by environment: minoxidil	Fig. 6 from Zhu et al., 2017
pronephros development decreased process quality, abnormal	pkd1a^{zf1067/zf1067} + MO4-atg5	standard conditions	Fig. 4 from Zhu et al., 2017
pronephric duct cystic, exacerbated	pkd1a^{zf1067/zf1067} + MO4-atg5	standard conditions	Fig. 4 from Zhu et al., 2017
pronephros development decreased process quality, abnormal	pkd1a^{zf1067/zf1067}; pkd1b^{zf1070/zf1070}	standard conditions	Fig. 1 from Zhu et al., 2017
pronephros development decreased process quality, exacerbated	pkd1a^{zf1067/zf1067}; pkd1b^{zf1070/zf1070}	standard conditions	Fig. 1 from Zhu et al., 2017
pronephric duct cystic, exacerbated	pkd1a^{zf1067/zf1067}; pkd1b^{zf1070/zf1070}	standard conditions	Fig. 1 from Zhu et al., 2017
pronephric duct cystic, abnormal	pkd1a^{zf1067/zf1067}; pkd1b^{zf1070/zf1070}	standard conditions	Fig. 1 from Zhu et al., 2017

Citations