TALEN

TALEN1-gba

ID
ZDB-TALEN-160129-1
Name
TALEN1-gba
Previous Names
None
Target
Target Sequence 1
5' - TCTGTACCCTGATTACTT - 3'
Target Sequence 2
5' - TGGACTCCACCCAGCGCAT - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
sh391 gba
Expression
Gene expression in Wild Types + TALEN1-gba
No data available
Phenotype
Phenotype resulting from TALEN1-gba
No data available
Phenotype of all Fish created by or utilizing TALEN1-gba
Phenotype Fish Conditions Figures
optic tectum microglial cell increased amount, abnormal gbash391/sh391 standard conditions Fig. 4 from Watson et al., 2019
microglial cell increased accumulation cerebellum, abnormal gbash391/sh391 standard conditions Fig. 4 from Watson et al., 2019
cerebellum microglial cell increased amount, abnormal gbash391/sh391 standard conditions Fig. 4 from Watson et al., 2019
brain tnfb expression increased amount, abnormal gbash391/sh391 standard conditions Fig. 1Fig. 3 from Watson et al., 2019
microglial cell increased accumulation optic tectum, abnormal gbash391/sh391 standard conditions Fig. 4 from Watson et al., 2019
brain cxcl8b.1 expression increased amount, abnormal gbash391/sh391 standard conditions Fig. 1Fig. 3 from Watson et al., 2019
brain cxcl8a expression increased amount, abnormal gbash391/sh391 standard conditions Fig. 1Fig. 3 from Watson et al., 2019
glucosylceramidase activity decreased process quality, abnormal gbash391/sh391(TL) standard conditions Fig. 1 from Keatinge et al., 2015
brain macrophage morphology, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
brain macrophage increased amount, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
thymus macrophage morphology, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
brain cytochrome-c oxidase activity decreased process quality, abnormal gbash391/sh391(TL) standard conditions Fig. 8 from Keatinge et al., 2015
brain autophagosome increased amount, abnormal gbash391/sh391(TL) standard conditions Fig. 8 from Keatinge et al., 2015
swimming decreased process quality, abnormal gbash391/sh391(TL) standard conditions Fig. 4 from Keatinge et al., 2015
liver macrophage increased amount, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
liver macrophage morphology, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
CNS neuron (sensu Vertebrata) inclusion body increased amount, abnormal gbash391/sh391(TL) standard conditions Fig. 7 from Keatinge et al., 2015
caudal periventricular hypothalamus dopaminergic neuron decreased amount, abnormal gbash391/sh391(TL) standard conditions Fig. 7 from Keatinge et al., 2015
tectal ventricle macrophage increased size, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
brain mitochondrion decreased functionality, abnormal gbash391/sh391(TL) standard conditions Fig. 8 from Keatinge et al., 2015
brain hexosaminidase activity increased process quality, abnormal gbash391/sh391(TL) standard conditions Fig. 3 from Keatinge et al., 2015
sphingolipid metabolic process disrupted, abnormal gbash391/sh391(TL) standard conditions Fig. 2 from Keatinge et al., 2015
macrophage increased accumulation tectal ventricle, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
brain chitinase activity increased process quality, abnormal gbash391/sh391(TL) standard conditions Fig. 3 from Keatinge et al., 2015
brain ubiquinol-cytochrome-c reductase activity decreased process quality, abnormal gbash391/sh391(TL) standard conditions Fig. 8 from Keatinge et al., 2015
spinal cord curved, abnormal gbash391/sh391(TL) standard conditions Fig. 3 from Keatinge et al., 2015
caudal tuberculum dopaminergic neuron decreased amount, abnormal gbash391/sh391(TL) standard conditions Fig. 7 from Keatinge et al., 2015
whole organism decreased life span, abnormal gbash391/sh391(TL) standard conditions text only from Keatinge et al., 2015
whole organism dead, abnormal gbash391/sh391(TL) standard conditions text only from Keatinge et al., 2015
brain glial cell projection retracted, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
brain microglial cell circular, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
microglial cell increased accumulation brain, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
thymus macrophage increased amount, abnormal gbash391/sh391(TL) standard conditions Fig. 5 from Keatinge et al., 2015
brain sncb expression decreased amount, abnormal gbash391/sh391(TL) standard conditions Fig. 7 from Keatinge et al., 2015
microglial cell spherical, abnormal gbash391/sh391 ; sh425Tg(TL) standard conditions Fig. 6 from Keatinge et al., 2015
brain mir155 expression increased amount, abnormal gbash391/sh391 ; sh425Tg(TL) standard conditions Fig. 6 from Keatinge et al., 2015
microglial cell activation increased occurrence, abnormal gbash391/sh391 ; sh425Tg(TL) standard conditions Fig. 6 from Keatinge et al., 2015
microglial cell vacuole increased amount, abnormal gbash391/sh391 ; sh425Tg(TL) standard conditions Fig. 6 from Keatinge et al., 2015
whole organism mir155 expression increased amount, abnormal gbash391/sh391 ; sh425Tg(TL) standard conditions Fig. 6 from Keatinge et al., 2015
microglial cell increased accumulation optic tectum, abnormal gbash391/sh391; mir155sh610/sh610 standard conditions Fig. 4 from Watson et al., 2019
brain cxcl8a expression increased amount, abnormal gbash391/sh391; mir155sh610/sh610 standard conditions Fig. 3 from Watson et al., 2019
microglial cell increased accumulation cerebellum, abnormal gbash391/sh391; mir155sh610/sh610 standard conditions Fig. 4 from Watson et al., 2019
cerebellum microglial cell increased amount, abnormal gbash391/sh391; mir155sh610/sh610 standard conditions Fig. 4 from Watson et al., 2019
optic tectum microglial cell increased amount, abnormal gbash391/sh391; mir155sh610/sh610 standard conditions Fig. 4 from Watson et al., 2019
brain tnfb expression increased amount, abnormal gbash391/sh391; mir155sh610/sh610 standard conditions Fig. 3 from Watson et al., 2019
brain cxcl8b.1 expression increased amount, abnormal gbash391/sh391; mir155sh610/sh610 standard conditions Fig. 3 from Watson et al., 2019
Citations