PUBLICATION
Compartmentalized expression of zebrafish ten-m3 and ten-m4, homologues of the Drosophila ten(m)/odd Oz gene, in the central nervous system
- Authors
- Mieda, M., Kikuchi, Y., Hirate, Y., Aoki, M., and Okamoto, H.
- ID
- ZDB-PUB-991020-9
- Date
- 1999
- Source
- Mechanisms of Development 87(1-2): 223-227 (Journal)
- Registered Authors
- Aoki, Yasunobu, Hirate, Yoshikazu, Kikuchi, Yutaka, Mieda, Michihiro, Okamoto, Hitoshi
- Keywords
- zebrafish; ten-m; teneurin; ten(m)/odd Oz (dz); DOC4; CNS; rhombomere; mesencephalon; diencephalon; midbrain/hindbrain boundary; EGF-repeat; tenascin
- MeSH Terms
-
- Tenascin/metabolism*
- DNA, Complementary/analysis
- Molecular Sequence Data
- Zebrafish Proteins*
- In Situ Hybridization
- Time Factors
- Mesencephalon/embryology
- Mesencephalon/metabolism*
- Amino Acid Sequence
- Gene Expression*
- Nerve Tissue Proteins/genetics
- Nerve Tissue Proteins/metabolism*
- Rhombencephalon/embryology
- Rhombencephalon/metabolism*
- Drosophila Proteins*
- Drosophila
- Zebrafish
- Animals
- Sequence Homology, Amino Acid
- PubMed
- 10495292 Full text @ Mech. Dev.
Citation
Mieda, M., Kikuchi, Y., Hirate, Y., Aoki, M., and Okamoto, H. (1999) Compartmentalized expression of zebrafish ten-m3 and ten-m4, homologues of the Drosophila ten(m)/odd Oz gene, in the central nervous system. Mechanisms of Development. 87(1-2):223-227.
Abstract
Zebrafish ten-m3 and ten-m4 encode proteins highly similar to the product of Drosophila pair-rule gene ten(m)/odd Oz (odz). Their products contain eight epidermal growth factor (EGF)-like repeats that resemble mostly those of the extracellular matrix molecule tenascin. During segmentation period, ten-m3 is expressed in the somites, notochord, pharyngeal arches, and the brain, while expression of ten-m4 is mainly restricted to the brain. In the developing brain, ten-m3 and ten-m4 expression delineates several compartments. Interestingly, ten-m3 and ten-m4 show expression patterns complementary to each other in the developing forebrain and midbrain along both rostrocaudal and dorsoventral axes, depending on developmental stages and locations.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping