PUBLICATION
sox30: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis
- Authors
- De Martino, S.P., Errington, F., Ashworth, A., Jowett, T., and Austin, C.A.
- ID
- ZDB-PUB-990628-17
- Date
- 1999
- Source
- Development genes and evolution 209(6): 357-362 (Journal)
- Registered Authors
- Austin, Caroline Ann, Jowett, Trevor
- Keywords
- sox; zebrafish; development; brain; midbrain-hindrain boundary
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Cloning, Molecular
- DNA, Complementary/chemistry
- DNA, Complementary/genetics
- DNA-Binding Proteins/genetics*
- Embryo, Nonmammalian/metabolism
- Evolution, Molecular
- Gene Expression Regulation, Developmental
- High Mobility Group Proteins/genetics*
- In Situ Hybridization
- Mesencephalon/embryology
- Mesencephalon/metabolism
- Molecular Sequence Data
- Nervous System/embryology
- Nervous System/metabolism
- Phylogeny
- RNA/genetics
- RNA/metabolism
- Rhombencephalon/embryology
- Rhombencephalon/metabolism
- SOXB2 Transcription Factors
- Sequence Alignment
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid
- Tissue Distribution
- Zebrafish
- Zebrafish Proteins*
- PubMed
- 10370117 Full text @ Dev. Genes Evol.
Citation
De Martino, S.P., Errington, F., Ashworth, A., Jowett, T., and Austin, C.A. (1999) sox30: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis. Development genes and evolution. 209(6):357-362.
Abstract
The Sox family of proteins is thought to act to regulate gene expression in a wide variety of developmental processes. Here we describe the cloning of sox30, a novel sox gene from the zebrafish (Danio rerio). In situ hybridization shows that sox30 is expressed in a restricted manner at the boundary between the midbrain and hindbrain during nervous system development. This expression pattern is in direct contrast to that of most other neuronally expressed Sox genes which are expressed throughout the nervous system.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping