PUBLICATION
Kidney development branches out
- Authors
- Dressler, G.R.
- ID
- ZDB-PUB-990525-12
- Date
- 1999
- Source
- Developmental genetics 24(3-4): 189-193 (Review)
- Registered Authors
- Dressler, Gregory R.
- Keywords
- kidney development; pronephros; Xenopus; zebrafish
- MeSH Terms
-
- Animals
- Disease Models, Animal
- Gene Expression Regulation, Developmental
- Humans
- Kidney/embryology
- Kidney/growth & development*
- Kidney Diseases/etiology
- Kidney Diseases/genetics
- Mice
- Models, Biological
- Xenopus laevis
- Zebrafish
- PubMed
- 10322626 Full text @ Dev. Genet.
Citation
Dressler, G.R. (1999) Kidney development branches out. Developmental genetics. 24(3-4):189-193.
Abstract
For more than 40 years now, the developing kidney has served as a model paradigm for epithelial-mesenchymal interactions. The principles of inductive signaling, epithelial cell differentiation, and pattern formation are now being addressed with modern genetic and biochemical tools. In addition to the mammalian kidney organ culture model, both zebrafish and Xenopus laevis demonstrate great potential for investigating the molecular mechanisms of kidney organogenesis within a whole organism. In this review, the papers presented in this special issue are discussed with respect to recent progress in the renal development field. Coincidentally, it has become increasingly clear that progress made in renal development can impact our understanding of the genetic basis of disease.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping