PUBLICATION
Expression of zkrml2, a homologue of the Krml1/val segmentation gene, during embryonic patterning of the zebrafish
- Authors
- Schvarzstein, M., Kirn, A., Haffter, P., and Cordes, S.P.
- ID
- ZDB-PUB-990427-17
- Date
- 1999
- Source
- Mechanisms of Development 80(2): 223-226 (Journal)
- Registered Authors
- Haffter, Pascal
- Keywords
- kreisler; valentino; basic domain leucine zipper; Maf protein; somitogenesis; myogenesis; zebrafish
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Avian Proteins*
- Chromosome Mapping
- DNA-Binding Proteins/biosynthesis
- DNA-Binding Proteins/genetics*
- Embryo, Nonmammalian/metabolism
- Embryo, Nonmammalian/ultrastructure
- Female
- Gene Expression Regulation, Developmental*
- Genes*
- Leucine Zippers/genetics
- Maf Transcription Factors
- MafB Transcription Factor
- Male
- Mesencephalon/embryology
- Mesencephalon/metabolism
- Mice
- Molecular Sequence Data
- Morphogenesis/genetics
- Mutagenesis
- Nerve Tissue Proteins/biosynthesis
- Nerve Tissue Proteins/genetics
- Neurons/metabolism
- Oncogene Proteins*
- Organ Specificity
- Proto-Oncogene Proteins/genetics
- Proto-Oncogene Proteins c-maf
- Rhombencephalon/embryology
- Rhombencephalon/metabolism
- Sequence Alignment
- Sequence Homology, Amino Acid
- Somites/metabolism*
- Species Specificity
- Transcription Factors/biosynthesis
- Transcription Factors/genetics*
- Zebrafish/embryology
- Zebrafish/genetics*
- Zebrafish Proteins*
- PubMed
- 10072793 Full text @ Mech. Dev.
Citation
Schvarzstein, M., Kirn, A., Haffter, P., and Cordes, S.P. (1999) Expression of zkrml2, a homologue of the Krml1/val segmentation gene, during embryonic patterning of the zebrafish. Mechanisms of Development. 80(2):223-226.
Abstract
We have identified Zkrml2, a novel homologue of the segmentation gene Krml/val in zebrafish (Danio rerio). Zkrml2 shows 72% and 92% identity in its basic leucine zipper domain with mouse Krml1 and zebrafish val, respectively. Zkrml2 is expressed coincident with MyoD throughout the somites starting at the three somite stage, becomes restricted to the dermomyotome, and subsequently disappears. Transient expression is also detected in the reticulospinal and oculomotor neurons. Zkrml2 maps to the Oregon linkage group 11 (Boston Linkage group 14) with no mapped zebrafish mutations nearby.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping